PTR1: a reductase mediating salvage of oxidized pteridines and methotrexate resistance in the protozoan parasite Leishmania major.

Ítems similars

• PTR1-dependent synthesis of tetrahydrobiopterin contributes to oxidant susceptibility in the trypanosomatid protozoan parasite Leishmania major
  per: Nare, Bakela, et al.
  Publicat: (2009)
• Increased transport of pteridines compensates for mutations in the high affinity folate transporter and contributes to methotrexate resistance in the protozoan parasite Leishmania tarentolae.
  per: Kündig, C, et al.
  Publicat: (1999)
• The Role of the Mitochondrial Glycine Cleavage Complex in the Metabolism and Virulence of the Protozoan Parasite Leishmania major
  per: Scott, David A., et al.
  Publicat: (2007)
• Dissecting the Metabolic Roles of Pteridine Reductase 1 in Trypanosoma brucei and Leishmania major
  per: Ong, Han B., et al.
  Publicat: (2011)
• Dual and selective inhibitors of pteridine reductase 1 (PTR1) and dihydrofolate reductase-thymidylate synthase (DHFR-TS) from Leishmania chagasi
  per: Bárbara Velame Ferreira Teixeira, et al.
  Publicat: (2019-01-01)