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Adenomatous polyposis coli is essential for both neuronal differentiation and maintenance of adult neural stem cells in subventricular zone and hippocampus

The tumor suppressor adenomatous polyposis coli (APC) is a multifunctional protein that not only inhibits the Wnt signaling pathway by promoting the degradation of beta-catenin but also controls cell polarity, motility, and division. APC is abundantly expressed in the adult central nervous system, b...

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Détails bibliographiques
Publié dans:Stem Cells
Auteurs principaux: Imura, Tetsuya, Wang, Xiaohong, Noda, Tetsuo, Sofroniew, Michael V., Fushiki, Shinji
Format: Artigo
Langue:Inglês
Publié: 2010
Sujets:
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC4524517/
https://ncbi.nlm.nih.gov/pubmed/21089118
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/stem.524
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