The Syk protein tyrosine kinase can function independently of CD45 or Lck in T cell antigen receptor signaling.

Lignende værker

• CD45 specifically modulates binding of Lck to a phosphopeptide encompassing the negative regulatory tyrosine of Lck.
  af: Sieh, M, et al.
  Udgivet: (1993)
• p56lck-independent activation and tyrosine phosphorylation of p72syk by T-cell antigen receptor/CD3 stimulation.
  af: Couture, C, et al.
  Udgivet: (1994)
• Tyrosine 192 within the SH2 domain of the Src-protein tyrosine kinase p56(Lck) regulates T-cell activation independently of Lck/CD45 interactions
  af: Kästle, Matthias, et al.
  Udgivet: (2020)
• Development of T-leukaemias in CD45 tyrosine phosphatase-deficient mutant lck mice
  af: Baker, Matthew, et al.
  Udgivet: (2000)
• Differential effects of expression of the CD45 tyrosine protein phosphatase on the tyrosine phosphorylation of the lck, fyn, and c-src tyrosine protein kinases.
  af: Hurley, T R, et al.
  Udgivet: (1993)