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The Syk protein tyrosine kinase can function independently of CD45 or Lck in T cell antigen receptor signaling.
The protein tyrosine phosphatase CD45 is a critical component of the T cell antigen receptor (TCR) signaling pathway, acting as a positive regulator of Src family protein tyrosine kinases (PTKs) such as Lck. Most CD45-deficient human and murine T cell lines are unable to signal through their TCRs. H...
Zapisane w:
| Wydane w: | EMBO J |
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| Główni autorzy: | , , , , , |
| Format: | Artigo |
| Język: | Inglês |
| Wydane: |
Nature Publishing Group
1996
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| Hasła przedmiotowe: | |
| Dostęp online: | https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC452448/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/8947048/ |
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