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Naive and radiolabeled antibodies to E6 and E7 HPV-16 oncoproteins show pronounced antitumor activity in experimental cervical cancer

BACKGROUND: In spite of profound reduction in incidence, cervical cancer claims >275,000 lives annually. Previously we demonstrated efficacy and safety of radioimmunotherapy directed at HPV16 E6 oncoprotein in experimental cervical cancer. MATERIALS & METHODS: We undertook a direct comparison...

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Detalhes bibliográficos
Publicado no:Immunotherapy
Main Authors: Phaëton, R, Gutierrez, J, Jiang, Z, Karabakhtsian, RG, Albanese, J, Sunkara, J, Fisher, DR, Goldberg, GL, Dadachova, E
Formato: Artigo
Idioma:Inglês
Publicado em: 2015
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4524293/
https://ncbi.nlm.nih.gov/pubmed/26098137
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2217/imt.15.18
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