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Radioimmunotherapy with an antibody to HPV16 E6 oncoprotein is effective in experimental cervical tumor expressing low levels of E6

PURPOSE: HPV16 is associated with ∼50% of all cervical cancers worldwide. The E6 and E7 genes of oncogenic HPV types, such as HPV16, are necessary for the HPV transforming function and tumorogenesis making them ideal targets for novel treatments. Radioimmunotherapy employs systemically administered...

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Detalhes bibliográficos
Main Authors: Phaeton, Rébécca, Harris, Matthew, Jiang, Zewei, Wang, Xing Guo, Einstein, Mark H, Goldberg, Gary L, Casadevall, Arturo, Dadachova, Ekaterina
Formato: Artigo
Idioma:Inglês
Publicado em: Landes Bioscience 2010
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3047096/
https://ncbi.nlm.nih.gov/pubmed/20861673
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4161/cbt.10.10.13322
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