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Early Steps of Jaagsiekte Sheep Retrovirus-Mediated Cell Transformation Involve the Interaction between Env and the RALBP1 Cellular Protein

Ovine pulmonary adenocarcinoma is a naturally occurring lung cancer in sheep induced by the Jaagsiekte sheep retrovirus (JSRV). Its envelope glycoprotein (Env) carries oncogenic properties, and its expression is sufficient to induce in vitro cell transformation and in vivo lung adenocarcinoma. The i...

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Publicat a:J Virol
Autors principals: Monot, Margaux, Erny, Alexandra, Gineys, Barbara, Desloire, Sophie, Dolmazon, Christine, Aublin-Gex, Anne, Lotteau, Vincent, Archer, Fabienne, Leroux, Caroline
Format: Artigo
Idioma:Inglês
Publicat: American Society for Microbiology 2015
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC4524258/
https://ncbi.nlm.nih.gov/pubmed/26041289
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.00590-15
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