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Expression of the Jaagsiekte Sheep Retrovirus Envelope Glycoprotein Is Sufficient To Induce Lung Tumors in Sheep

Jaagsiekte sheep retrovirus (JSRV) is the causative agent of ovine pulmonary adenocarcinoma (OPA). The expression of the JSRV envelope (Env) alone is sufficient to transform a variety of cell lines in vitro and induce lung cancer in immunodeficient mice. In order to determine the role of the JSRV En...

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Detalhes bibliográficos
Main Authors: Caporale, Marco, Cousens, Christina, Centorame, Patrizia, Pinoni, Chiara, De las Heras, Marcelo, Palmarini, Massimo
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology 2006
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC1563803/
https://ncbi.nlm.nih.gov/pubmed/16873259
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.00474-06
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