Expression of the Jaagsiekte Sheep Retrovirus Envelope Glycoprotein Is Sufficient To Induce Lung Tumors in Sheep

Jaagsiekte sheep retrovirus (JSRV) is the causative agent of ovine pulmonary adenocarcinoma (OPA). The expression of the JSRV envelope (Env) alone is sufficient to transform a variety of cell lines in vitro and induce lung cancer in immunodeficient mice. In order to determine the role of the JSRV En...

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Sonraí Bibleagrafaíochta
Main Authors: Caporale, Marco, Cousens, Christina, Centorame, Patrizia, Pinoni, Chiara, De las Heras, Marcelo, Palmarini, Massimo
Formáid: Artigo
Teanga:Inglês
Foilsithe: American Society for Microbiology 2006
Ábhair:
Transformation and Oncogenesis
Rochtain Ar Líne:https://ncbi.nlm.nih.gov/pmc/articles/PMC1563803/
https://ncbi.nlm.nih.gov/pubmed/16873259
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.00474-06
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