Restriction of HIV-1 Requires the N-Terminal Region of MxB as a Capsid-Binding Motif but Not as a Nuclear Localization Signal

The interferon alpha (IFN-α)-inducible restriction factor MxB blocks HIV-1 infection after reverse transcription but prior to integration. Fate-of-capsid experiments have correlated the ability of MxB to block HIV-1 infection with stabilization of viral cores during infection. We previously demonstr...

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Veröffentlicht in:J Virol
Hauptverfasser: Schulte, Bianca, Buffone, Cindy, Opp, Silvana, Di Nunzio, Francesca, De Souza Aranha Vieira, Daniel Augusto, Brandariz-Nuñez, Alberto, Diaz-Griffero, Felipe
Format: Artigo
Sprache:Inglês
Veröffentlicht: American Society for Microbiology 2015
Schlagworte:
Virus-Cell Interactions
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4524248/
https://ncbi.nlm.nih.gov/pubmed/26063425
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.00753-15
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