Vaccine-Induced Linear Epitope-Specific Antibodies to Simian Immunodeficiency Virus SIVmac239 Envelope Are Distinct from Those Induced to the Human Immunodeficiency Virus Type 1 Envelope in Nonhuman Primates

To evaluate antibody specificities induced by simian immunodeficiency virus (SIV) versus human immunodeficiency virus type 1 (HIV-1) envelope antigens in nonhuman primate (NHP), we profiled binding antibody responses to linear epitopes in NHP studies with HIV-1 or SIV immunogens. We found that, over...

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Publicado en:J Virol
Main Authors: Shen, Xiaoying, Duffy, Ryan, Howington, Robert, Cope, Alethea, Sadagopal, Shanmugalakshmi, Park, Haesun, Pal, Ranajit, Kwa, Suefen, Ding, Song, Yang, Otto O., Fouda, Genevieve G., Le Grand, Roger, Bolton, Diane, Esteban, Mariano, Phogat, Sanjay, Roederer, Mario, Amara, Rama R., Picker, Louis J., Seder, Robert A., McElrath, M. Juliana, Barnett, Susan, Permar, Sallie R., Shattock, Robin, DeVico, Anthony L., Felber, Barbara K., Pavlakis, George N., Pantaleo, Giuseppe, Korber, Bette T., Montefiori, David C., Tomaras, Georgia D.
Formato: Artigo
Idioma:Inglês
Publicado: American Society for Microbiology 2015
Assuntos:
Vaccines and Antiviral Agents
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC4524233/
https://ncbi.nlm.nih.gov/pubmed/26018159
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.03635-14
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