Vaccine-Induced Linear Epitope-Specific Antibodies to Simian Immunodeficiency Virus SIVmac239 Envelope Are Distinct from Those Induced to the Human Immunodeficiency Virus Type 1 Envelope in Nonhuman Primates

To evaluate antibody specificities induced by simian immunodeficiency virus (SIV) versus human immunodeficiency virus type 1 (HIV-1) envelope antigens in nonhuman primate (NHP), we profiled binding antibody responses to linear epitopes in NHP studies with HIV-1 or SIV immunogens. We found that, over...

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發表在:J Virol
Main Authors: Shen, Xiaoying, Duffy, Ryan, Howington, Robert, Cope, Alethea, Sadagopal, Shanmugalakshmi, Park, Haesun, Pal, Ranajit, Kwa, Suefen, Ding, Song, Yang, Otto O., Fouda, Genevieve G., Le Grand, Roger, Bolton, Diane, Esteban, Mariano, Phogat, Sanjay, Roederer, Mario, Amara, Rama R., Picker, Louis J., Seder, Robert A., McElrath, M. Juliana, Barnett, Susan, Permar, Sallie R., Shattock, Robin, DeVico, Anthony L., Felber, Barbara K., Pavlakis, George N., Pantaleo, Giuseppe, Korber, Bette T., Montefiori, David C., Tomaras, Georgia D.
格式: Artigo
語言:Inglês
出版: American Society for Microbiology 2015
主題:
Vaccines and Antiviral Agents
在線閱讀:https://ncbi.nlm.nih.gov/pmc/articles/PMC4524233/
https://ncbi.nlm.nih.gov/pubmed/26018159
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.03635-14
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