Protective Efficacy of Recombinant Modified Vaccinia Virus Ankara Delivering Middle East Respiratory Syndrome Coronavirus Spike Glycoprotein

Middle East respiratory syndrome coronavirus (MERS-CoV) causes severe respiratory disease in humans. We tested a recombinant modified vaccinia virus Ankara (MVA) vaccine expressing full-length MERS-CoV spike (S) glycoprotein by immunizing BALB/c mice with either intramuscular or subcutaneous regimen...

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Vydáno v:J Virol
Hlavní autoři: Volz, Asisa, Kupke, Alexandra, Song, Fei, Jany, Sylvia, Fux, Robert, Shams-Eldin, Hosam, Schmidt, Jörg, Becker, Christin, Eickmann, Markus, Becker, Stephan, Sutter, Gerd
Médium: Artigo
Jazyk:Inglês
Vydáno: American Society for Microbiology 2015
Témata:
Vaccines and Antiviral Agents
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC4524222/
https://ncbi.nlm.nih.gov/pubmed/26018172
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.00614-15
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