Human Schlafen 5 (SLFN5) Is a Regulator of Motility and Invasiveness of Renal Cell Carcinoma Cells

We provide evidence that human SLFN5, an interferon (IFN)-inducible member of the Schlafen (SLFN) family of proteins, exhibits key roles in controlling motility and invasiveness of renal cell carcinoma (RCC) cells. Our studies define the mechanism by which this occurs, demonstrating that SLFN5 negat...

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Vydáno v:Mol Cell Biol
Hlavní autoři: Sassano, Antonella, Mavrommatis, Evangelos, Arslan, Ahmet Dirim, Kroczynska, Barbara, Beauchamp, Elspeth M., Khuon, Satya, Chew, Ten-Leong, Green, Kathleen J., Munshi, Hidayatullah G., Verma, Amit K., Platanias, Leonidas C.
Médium: Artigo
Jazyk:Inglês
Vydáno: American Society for Microbiology 2015
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On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC4524119/
https://ncbi.nlm.nih.gov/pubmed/26012550
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/MCB.00019-15
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