Human Schlafen 5 (SLFN5) Is a Regulator of Motility and Invasiveness of Renal Cell Carcinoma Cells

We provide evidence that human SLFN5, an interferon (IFN)-inducible member of the Schlafen (SLFN) family of proteins, exhibits key roles in controlling motility and invasiveness of renal cell carcinoma (RCC) cells. Our studies define the mechanism by which this occurs, demonstrating that SLFN5 negat...

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Pubblicato in:Mol Cell Biol
Autori principali: Sassano, Antonella, Mavrommatis, Evangelos, Arslan, Ahmet Dirim, Kroczynska, Barbara, Beauchamp, Elspeth M., Khuon, Satya, Chew, Ten-Leong, Green, Kathleen J., Munshi, Hidayatullah G., Verma, Amit K., Platanias, Leonidas C.
Natura: Artigo
Lingua:Inglês
Pubblicazione: American Society for Microbiology 2015
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Articles
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC4524119/
https://ncbi.nlm.nih.gov/pubmed/26012550
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/MCB.00019-15
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