Cell- and Protein-Directed Glycosylation of Native Cleaved HIV-1 Envelope

The gp120/gp41 HIV-1 envelope glycoprotein (Env) is highly glycosylated, with up to 50% of its mass consisting of N-linked glycans. This dense carbohydrate coat has emerged as a promising vaccine target, with its glycans acting as epitopes for a number of potent and broadly neutralizing antibodies (...

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Detaylı Bibliyografya
Yayımlandı:J Virol
Asıl Yazarlar: Pritchard, Laura K., Harvey, David J., Bonomelli, Camille, Crispin, Max, Doores, Katie J.
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: American Society for Microbiology 2015
Konular:
Vaccines and Antiviral Agents
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC4524065/
https://ncbi.nlm.nih.gov/pubmed/26085151
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.01190-15
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