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Structural principles controlling HIV envelope glycosylation

The heavily glycosylated, trimeric HIV-1 envelope (Env) protein is the sole viral protein exposed on the HIV-1 virion surface and is thus a main focus of antibody-mediated vaccine development. Dense glycosylation at the outer domain of Env constrains normal enzymatic processing, stalling the glycans...

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Detalles Bibliográficos
Publicado en:Curr Opin Struct Biol
Main Authors: Behrens, Anna-Janina, Crispin, Max
Formato: Artigo
Idioma:Inglês
Publicado: 2017
Assuntos:
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC5513759/
https://ncbi.nlm.nih.gov/pubmed/28363124
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.sbi.2017.03.008
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