Broadly protective immunity against divergent influenza viruses by oral co-administration of Lactococcus lactis expressing nucleoprotein adjuvanted with cholera toxin B subunit in mice

BACKGROUND: Current influenza vaccines need to be annually reformulated to well match the predicated circulating strains. Thus, it is critical for developing a novel universal influenza vaccine that would be able to confer cross-protection against constantly emerging divergent influenza virus strain...

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Detalhes bibliográficos
Publicado no:Microb Cell Fact
Main Authors: Lei, Han, Peng, Xiaojue, Jiao, Huifeng, Zhao, Daxian, Ouyang, Jiexiu
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2015
Assuntos:
Research
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4524015/
https://ncbi.nlm.nih.gov/pubmed/26242406
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12934-015-0287-4
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