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Evaluation of Oral Immunization with Recombinant Avian Influenza Virus HA1 Displayed on the Lactococcus lactis Surface and Combined with the Mucosal Adjuvant Cholera Toxin Subunit B

The development of safe and efficient avian influenza vaccines for human and animal uses is essential for preventing virulent outbreaks and pandemics worldwide. In this study, we constructed a recombinant (pgsA-HA1 gene fusion) Lactococcus lactis strain that expresses and displays the avian influenz...

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Main Authors: Lei, Han, Sheng, Zhina, Ding, Qian, Chen, Jian, Wei, Xiaohui, Lam, Dominic Man-Kit, Xu, Yuhong
Formato: Artigo
Idioma:Inglês
Publicado: American Society for Microbiology 2011
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC3147322/
https://ncbi.nlm.nih.gov/pubmed/21632890
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/CVI.00050-11
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