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Mitochondrial DAMPS released by abdominal trauma suppress pulmonary immune responses

OBJECTIVES: Historically fever, pneumonia and sepsis after trauma are ascribed to pain and poor pulmonary toilet. No evidence supports that assertion however, and no known biologic mechanisms link injury to infection. Our studies show injured tissues release mitochondria (MT). Mitochondrial danger-a...

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Detalhes bibliográficos
Publicado no:J Trauma Acute Care Surg
Main Authors: Zhao, Cong, Itagaki, Kiyoshi, Gupta, Alok, Odom, Stephen, Sandler, Nicola, Hauser, Carl J.
Formato: Artigo
Idioma:Inglês
Publicado em: 2014
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4523560/
https://ncbi.nlm.nih.gov/pubmed/24747452
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1097/TA.0000000000000220
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