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Mitochondrial DAMPS released by abdominal trauma suppress pulmonary immune responses

OBJECTIVES: Historically fever, pneumonia and sepsis after trauma are ascribed to pain and poor pulmonary toilet. No evidence supports that assertion however, and no known biologic mechanisms link injury to infection. Our studies show injured tissues release mitochondria (MT). Mitochondrial danger-a...

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Bibliographische Detailangaben
Veröffentlicht in:J Trauma Acute Care Surg
Hauptverfasser: Zhao, Cong, Itagaki, Kiyoshi, Gupta, Alok, Odom, Stephen, Sandler, Nicola, Hauser, Carl J.
Format: Artigo
Sprache:Inglês
Veröffentlicht: 2014
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4523560/
https://ncbi.nlm.nih.gov/pubmed/24747452
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1097/TA.0000000000000220
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