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Hypoxia inducible factor 1α contributes to regulation of autophagy in retinal detachment

Photoreceptor (PR) cells receive oxygen and nutritional support from the underlying retinal pigment epithelium (RPE). Retinal detachment results in PR hypoxia and their time-dependent death. Detachment also activates autophagy within the PR, which serves to reduce the rate of PR apoptosis. In this s...

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Dades bibliogràfiques
Publicat a:Exp Eye Res
Autors principals: Shelby, Shameka J., Angadi, Pavan S., Zheng, Qiong-Duon, Yao, Jingyu, Jia, Lin, Zacks, David N.
Format: Artigo
Idioma:Inglês
Publicat: 2015
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC4523440/
https://ncbi.nlm.nih.gov/pubmed/26093278
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.exer.2015.06.016
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