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Hypoxia inducible factor 1α contributes to regulation of autophagy in retinal detachment

Photoreceptor (PR) cells receive oxygen and nutritional support from the underlying retinal pigment epithelium (RPE). Retinal detachment results in PR hypoxia and their time-dependent death. Detachment also activates autophagy within the PR, which serves to reduce the rate of PR apoptosis. In this s...

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Detalhes bibliográficos
Publicado no:Exp Eye Res
Main Authors: Shelby, Shameka J., Angadi, Pavan S., Zheng, Qiong-Duon, Yao, Jingyu, Jia, Lin, Zacks, David N.
Formato: Artigo
Idioma:Inglês
Publicado em: 2015
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4523440/
https://ncbi.nlm.nih.gov/pubmed/26093278
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.exer.2015.06.016
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