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Hypoxia inducible factor 1α contributes to regulation of autophagy in retinal detachment
Photoreceptor (PR) cells receive oxygen and nutritional support from the underlying retinal pigment epithelium (RPE). Retinal detachment results in PR hypoxia and their time-dependent death. Detachment also activates autophagy within the PR, which serves to reduce the rate of PR apoptosis. In this s...
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Publicado no: | Exp Eye Res |
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Main Authors: | , , , , , |
Formato: | Artigo |
Idioma: | Inglês |
Publicado em: |
2015
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Assuntos: | |
Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4523440/ https://ncbi.nlm.nih.gov/pubmed/26093278 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.exer.2015.06.016 |
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