Identification of calcium binding sites that regulate potentiation of a neuronal nicotinic acetylcholine receptor.

The divalent cation calcium potentiates the physiological response of neuronal nicotinic receptors to agonists by enhancing ionic current amplitudes, apparent agonist affinity and cooperativity. Here we show that mutations in several consensus Ca2+ binding sequences from the N-terminal domain of the...

Deskribapen osoa

Gorde:
Xehetasun bibliografikoak
Argitaratua izan da:EMBO J
Egile Nagusiak: Galzi, J L, Bertrand, S, Corringer, P J, Changeux, J P, Bertrand, D
Formatua: Artigo
Hizkuntza:Inglês
Argitaratua: Nature Publishing Group 1996
Gaiak:
Research Article
Sarrera elektronikoa:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC452330/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/8918460/
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