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Amodiaquine, an antimalarial drug, inhibits dengue virus type 2 replication and infectivity

Dengue virus serotypes 1–4 (DENV1–4) are transmitted by mosquitoes which cause most frequent arboviral infections in the world resulting in ∼390 million cases with ∼25,000 deaths annually. There is no vaccine or antiviral drug currently available for human use. Compounds containing quinoline scaffol...

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Detalhes bibliográficos
Publicado no:Antiviral Res
Main Authors: Boonyasuppayakorn, Siwaporn, Reichert, Erin D., Manzano, Mark, Nagarajan, Kuppuswamy, Padmanabhan, Radhakrishnan
Formato: Artigo
Idioma:Inglês
Publicado em: Elsevier B.V. 2014
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4523242/
https://ncbi.nlm.nih.gov/pubmed/24680954
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.antiviral.2014.03.014
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