Identification of Cis-Acting Elements in the 3′-Untranslated Region of the Dengue Virus Type 2 RNA That Modulate Translation and Replication

Using the massively parallel genetic algorithm for RNA folding, we show that the core region of the 3′-untranslated region of the dengue virus (DENV) RNA can form two dumbbell structures (5′- and 3′-DBs) of unequal frequencies of occurrence. These structures have the propensity to form two potential...

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Autores principales: Manzano, Mark, Reichert, Erin D., Polo, Stephanie, Falgout, Barry, Kasprzak, Wojciech, Shapiro, Bruce A., Padmanabhan, Radhakrishnan
Formato: Artigo
Lenguaje:Inglês
Publicado: American Society for Biochemistry and Molecular Biology 2011
Materias:
Microbiology
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC3121397/
https://ncbi.nlm.nih.gov/pubmed/21515677
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M111.234302
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