Structural complexity of Dengue virus untranslated regions: cis-acting RNA motifs and pseudoknot interactions modulating functionality of the viral genome

The Dengue virus (DENV) genome contains multiple cis-acting elements required for translation and replication. Previous studies indicated that a 719-nt subgenomic minigenome (DENV-MINI) is an efficient template for translation and (−) strand RNA synthesis in vitro. We performed a detailed structural...

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Bibliographic Details
Main Authors: Sztuba-Solinska, Joanna, Teramoto, Tadahisa, Rausch, Jason W., Shapiro, Bruce A., Padmanabhan, Radhakrishnan, Le Grice, Stuart F. J.
Format: Artigo
Language:Inglês
Published: Oxford University Press 2013
Subjects:
RNA
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC3643606/
https://ncbi.nlm.nih.gov/pubmed/23531545
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/nar/gkt203
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