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Self-assembled Messenger RNA Nanoparticles (mRNA-NPs) for Efficient Gene Expression

Although mRNA has several advantages over plasmid DNA when delivered into cells for gene expression, mRNA transfection is a very rare occurrence in gene delivery. This is mainly because of the labile nature of RNA, resulting in a low expression level of the desired protein. In this study, self-assem...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Veröffentlicht in:Sci Rep
Hauptverfasser: Kim, Hyejin, Park, Yongkuk, Lee, Jong Bum
Format: Artigo
Sprache:Inglês
Veröffentlicht: Nature Publishing Group 2015
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4522648/
https://ncbi.nlm.nih.gov/pubmed/26235529
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/srep12737
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