Effect of methylphenidate treatment during adolescence on norepinephrine transporter function in orbitofrontal cortex in a rat model of Attention Deficit Hyperactivity Disorder

Attention Deficit Hyperactivity Disorder (ADHD) is associated with hypofunctional medial prefrontal cortex (mPFC) and orbitofrontal cortex (OFC). Methylphenidate (MPH) remediates ADHD, in part, by inhibiting the norepinephrine transporter (NET). MPH also reduces ADHD-like symptoms in Spontaneously H...

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Pubblicato in:J Neurosci Methods
Autori principali: Somkuwar, Sucharita S., Kantak, Kathleen M., Dwoskin, Linda P.
Natura: Artigo
Lingua:Inglês
Pubblicazione: 2015
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Article
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC4522381/
https://ncbi.nlm.nih.gov/pubmed/25680322
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.jneumeth.2015.02.002
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