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Methylphenidate treatment beyond adolescence maintains increased cocaine self-administration in the Spontaneously Hypertensive Rat model of Attention Deficit/Hyperactivity Disorder

Past research with the Spontaneously Hypertensive Rat (SHR) model of Attention Deficit/Hyperactivity Disorder showed that adolescent methylphenidate treatment enhanced cocaine abuse risk in SHR during adulthood. Acquisition of cocaine self-administration was faster, and cocaine dose-response functio...

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Bibliographic Details
Published in:Pharmacol Biochem Behav
Main Authors: Baskin, Britahny M., Dwoskin, Linda P., Kantak, Kathleen M.
Format: Artigo
Language:Inglês
Published: 2015
Subjects:
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC4369437/
https://ncbi.nlm.nih.gov/pubmed/25643872
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.pbb.2015.01.019
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