Effect of methylphenidate treatment during adolescence on norepinephrine transporter function in orbitofrontal cortex in a rat model of Attention Deficit Hyperactivity Disorder

Attention Deficit Hyperactivity Disorder (ADHD) is associated with hypofunctional medial prefrontal cortex (mPFC) and orbitofrontal cortex (OFC). Methylphenidate (MPH) remediates ADHD, in part, by inhibiting the norepinephrine transporter (NET). MPH also reduces ADHD-like symptoms in Spontaneously H...

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Publicat a:J Neurosci Methods
Autors principals: Somkuwar, Sucharita S., Kantak, Kathleen M., Dwoskin, Linda P.
Format: Artigo
Idioma:Inglês
Publicat: 2015
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Article
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC4522381/
https://ncbi.nlm.nih.gov/pubmed/25680322
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.jneumeth.2015.02.002
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