Effect of methylphenidate treatment during adolescence on norepinephrine transporter function in orbitofrontal cortex in a rat model of Attention Deficit Hyperactivity Disorder

Attention Deficit Hyperactivity Disorder (ADHD) is associated with hypofunctional medial prefrontal cortex (mPFC) and orbitofrontal cortex (OFC). Methylphenidate (MPH) remediates ADHD, in part, by inhibiting the norepinephrine transporter (NET). MPH also reduces ADHD-like symptoms in Spontaneously H...

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Publicado en:J Neurosci Methods
Autores principales: Somkuwar, Sucharita S., Kantak, Kathleen M., Dwoskin, Linda P.
Formato: Artigo
Lenguaje:Inglês
Publicado: 2015
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Article
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC4522381/
https://ncbi.nlm.nih.gov/pubmed/25680322
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.jneumeth.2015.02.002
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