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Yet another job for Dna2: checkpoint activation

Mec1 (ATR in humans) is the principal kinase responsible for checkpoint activation in response to replication stress and DNA damage in Saccharomyces cerevisiae. Checkpoint initiation requires stimulation of Mec1 kinase activity by specific activators. The complexity of checkpoint initiation in yeast...

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Foilsithe in:DNA Repair (Amst)
Main Authors: Wanrooij, Paulina H., Burgers, Peter M.
Formáid: Artigo
Teanga:Inglês
Foilsithe: 2015
Ábhair:
Rochtain Ar Líne:https://ncbi.nlm.nih.gov/pmc/articles/PMC4522331/
https://ncbi.nlm.nih.gov/pubmed/25956863
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.dnarep.2015.04.009
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