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Yet another job for Dna2: checkpoint activation
Mec1 (ATR in humans) is the principal kinase responsible for checkpoint activation in response to replication stress and DNA damage in Saccharomyces cerevisiae. Checkpoint initiation requires stimulation of Mec1 kinase activity by specific activators. The complexity of checkpoint initiation in yeast...
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| Publicat a: | DNA Repair (Amst) |
|---|---|
| Autors principals: | , |
| Format: | Artigo |
| Idioma: | Inglês |
| Publicat: |
2015
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| Matèries: | |
| Accés en línia: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4522331/ https://ncbi.nlm.nih.gov/pubmed/25956863 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.dnarep.2015.04.009 |
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