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The hidden side of unstable DNA repeats: mutagenesis at a distance

Structure-prone DNA repeats are common components of genomic DNA in all kingdoms of life. In humans, these repeats are linked to genomic instabilities that result in various hereditary disorders, including many cancers. It has long been known that DNA repeats are not only highly polymorphic in lengt...

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Vydáno v:DNA Repair (Amst)
Hlavní autoři: Shah, Kartik A., Mirkin, Sergei M.
Médium: Artigo
Jazyk:Inglês
Vydáno: 2015
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC4522329/
https://ncbi.nlm.nih.gov/pubmed/25956860
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.dnarep.2015.04.020
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