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Replication stalling at unstable inverted repeats: Interplay between DNA hairpins and fork stabilizing proteins

DNA inverted repeats (IRs) are hotspots of genomic instability in both prokaryotes and eukaryotes. This feature is commonly attributed to their ability to fold into hairpin- or cruciform-like DNA structures interfering with DNA replication and other genetic processes. However, direct evidence that I...

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Hlavní autoři: Voineagu, Irina, Narayanan, Vidhya, Lobachev, Kirill S., Mirkin, Sergei M.
Médium: Artigo
Jazyk:Inglês
Vydáno: National Academy of Sciences 2008
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC2481305/
https://ncbi.nlm.nih.gov/pubmed/18632578
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0804510105
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