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Prediction of problematic complexes from PPI networks: sparse, embedded, and small complexes

BACKGROUND: The prediction of protein complexes from high-throughput protein-protein interaction (PPI) data remains an important challenge in bioinformatics. Three groups of complexes have been identified as problematic to discover. First, many complexes are sparsely connected in the PPI network, an...

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Detalles Bibliográficos
Publicado en:Biol Direct
Autores principales: Yong, Chern Han, Wong, Limsoon
Formato: Artigo
Lenguaje:Inglês
Publicado: BioMed Central 2015
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Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC4522147/
https://ncbi.nlm.nih.gov/pubmed/26231465
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s13062-015-0067-4
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