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Prediction of problematic complexes from PPI networks: sparse, embedded, and small complexes

BACKGROUND: The prediction of protein complexes from high-throughput protein-protein interaction (PPI) data remains an important challenge in bioinformatics. Three groups of complexes have been identified as problematic to discover. First, many complexes are sparsely connected in the PPI network, an...

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Detalhes bibliográficos
Publicado no:Biol Direct
Main Authors: Yong, Chern Han, Wong, Limsoon
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2015
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4522147/
https://ncbi.nlm.nih.gov/pubmed/26231465
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s13062-015-0067-4
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