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Prediction of problematic complexes from PPI networks: sparse, embedded, and small complexes

BACKGROUND: The prediction of protein complexes from high-throughput protein-protein interaction (PPI) data remains an important challenge in bioinformatics. Three groups of complexes have been identified as problematic to discover. First, many complexes are sparsely connected in the PPI network, an...

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Dades bibliogràfiques
Publicat a:Biol Direct
Autors principals: Yong, Chern Han, Wong, Limsoon
Format: Artigo
Idioma:Inglês
Publicat: BioMed Central 2015
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC4522147/
https://ncbi.nlm.nih.gov/pubmed/26231465
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s13062-015-0067-4
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