Preferential Interactions and the Effect of Protein PEGylation

BACKGROUND: PEGylation is a strategy used by the pharmaceutical industry to prolong systemic circulation of protein drugs, whereas formulation excipients are used for stabilization of proteins during storage. Here we investigate the role of PEGylation in protein stabilization by formulation excipien...

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Pubblicato in:PLoS One
Autori principali: Holm, Louise Stenstrup, Thulstrup, Peter W., Kasimova, Marina R., van de Weert, Marco
Natura: Artigo
Lingua:Inglês
Pubblicazione: Public Library of Science 2015
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Research Article
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC4521882/
https://ncbi.nlm.nih.gov/pubmed/26230338
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0133584
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