Preferential Interactions and the Effect of Protein PEGylation

BACKGROUND: PEGylation is a strategy used by the pharmaceutical industry to prolong systemic circulation of protein drugs, whereas formulation excipients are used for stabilization of proteins during storage. Here we investigate the role of PEGylation in protein stabilization by formulation excipien...

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Publicat a:PLoS One
Autors principals: Holm, Louise Stenstrup, Thulstrup, Peter W., Kasimova, Marina R., van de Weert, Marco
Format: Artigo
Idioma:Inglês
Publicat: Public Library of Science 2015
Matèries:
Research Article
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC4521882/
https://ncbi.nlm.nih.gov/pubmed/26230338
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0133584
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