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Preferential Interactions and the Effect of Protein PEGylation

BACKGROUND: PEGylation is a strategy used by the pharmaceutical industry to prolong systemic circulation of protein drugs, whereas formulation excipients are used for stabilization of proteins during storage. Here we investigate the role of PEGylation in protein stabilization by formulation excipien...

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Publié dans:PLoS One
Auteurs principaux: Holm, Louise Stenstrup, Thulstrup, Peter W., Kasimova, Marina R., van de Weert, Marco
Format: Artigo
Langue:Inglês
Publié: Public Library of Science 2015
Sujets:
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC4521882/
https://ncbi.nlm.nih.gov/pubmed/26230338
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0133584
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