Wingless inactivates glycogen synthase kinase-3 via an intracellular signalling pathway which involves a protein kinase C.

The Drosophila gene product Wingless (Wg) is a secreted glycoprotein and a member of the Wnt gene family. Genetic analysis of Drosophila epidermal development has defined a putative paracrine Wg signalling pathway involving the zeste-white 3/shaggy (zw3/sgg) gene product. Although putative component...

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Bibliographic Details
Main Authors: Cook, D, Fry, M J, Hughes, K, Sumathipala, R, Woodgett, J R, Dale, T C
Format: Artigo
Language:Inglês
Published: 1996
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Research Article
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC452182/
https://ncbi.nlm.nih.gov/pubmed/8887544
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