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Wingless inactivates glycogen synthase kinase-3 via an intracellular signalling pathway which involves a protein kinase C.

The Drosophila gene product Wingless (Wg) is a secreted glycoprotein and a member of the Wnt gene family. Genetic analysis of Drosophila epidermal development has defined a putative paracrine Wg signalling pathway involving the zeste-white 3/shaggy (zw3/sgg) gene product. Although putative component...

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Udgivet i:EMBO J
Principais autores: Cook, D, Fry, M J, Hughes, K, Sumathipala, R, Woodgett, J R, Dale, T C
Format: Artigo
Sprog:Inglês
Udgivet: Nature Publishing Group 1996
Fag:
Research Article
Online adgang:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC452182/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/8887544/
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