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A Genetic Incompatibility Accelerates Adaptation in Yeast

During mismatch repair (MMR) MSH proteins bind to mismatches that form as the result of DNA replication errors and recruit MLH factors such as Mlh1-Pms1 to initiate excision and repair steps. Previously, we identified a negative epistatic interaction involving naturally occurring polymorphisms in th...

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發表在:PLoS Genet
Main Authors: Bui, Duyen T., Dine, Elliot, Anderson, James B., Aquadro, Charles F., Alani, Eric E.
格式: Artigo
語言:Inglês
出版: Public Library of Science 2015
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在線閱讀:https://ncbi.nlm.nih.gov/pmc/articles/PMC4521705/
https://ncbi.nlm.nih.gov/pubmed/26230253
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pgen.1005407
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