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A Genetic Incompatibility Accelerates Adaptation in Yeast

During mismatch repair (MMR) MSH proteins bind to mismatches that form as the result of DNA replication errors and recruit MLH factors such as Mlh1-Pms1 to initiate excision and repair steps. Previously, we identified a negative epistatic interaction involving naturally occurring polymorphisms in th...

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Detalhes bibliográficos
Publicado no:PLoS Genet
Main Authors: Bui, Duyen T., Dine, Elliot, Anderson, James B., Aquadro, Charles F., Alani, Eric E.
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2015
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4521705/
https://ncbi.nlm.nih.gov/pubmed/26230253
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pgen.1005407
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