Promoters of Human Cosmc and T-synthase Genes Are Similar in Structure, Yet Different in Epigenetic Regulation

The T-synthase (core 1 β3-galactosyltransferase) and its molecular chaperone Cosmc regulate the biosynthesis of mucin type O-glycans on glycoproteins, and evidence suggests that both T-synthase and Cosmc are transcriptionally suppressed in several human diseases, although the transcriptional regulat...

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Detalhes bibliográficos
Publicado no:J Biol Chem
Main Authors: Zeng, Junwei, Mi, Rongjuan, Wang, Yingchun, Li, Yujing, Lin, Li, Yao, Bing, Song, Lina, van Die, Irma, Chapman, Arlene B., Cummings, Richard D., Jin, Peng, Ju, Tongzhong
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Biochemistry and Molecular Biology 2015
Assuntos:
Gene Regulation
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4521027/
https://ncbi.nlm.nih.gov/pubmed/26063800
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M115.654244
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