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The Role of Copper and Zinc Toxicity in Innate Immune Defense against Bacterial Pathogens

Zinc (Zn) and copper (Cu) are essential for optimal innate immune function, and nutritional deficiency in either metal leads to increased susceptibility to bacterial infection. Recently, the decreased survival of bacterial pathogens with impaired Cu and/or Zn detoxification systems in phagocytes and...

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Библиографические подробности
Опубликовано в: :J Biol Chem
Главные авторы: Djoko, Karrera Y., Ong, Cheryl-lynn Y., Walker, Mark J., McEwan, Alastair G.
Формат: Artigo
Язык:Inglês
Опубликовано: American Society for Biochemistry and Molecular Biology 2015
Предметы:
Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC4521016/
https://ncbi.nlm.nih.gov/pubmed/26055706
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.R115.647099
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