The Role of Copper and Zinc Toxicity in Innate Immune Defense against Bacterial Pathogens

Zinc (Zn) and copper (Cu) are essential for optimal innate immune function, and nutritional deficiency in either metal leads to increased susceptibility to bacterial infection. Recently, the decreased survival of bacterial pathogens with impaired Cu and/or Zn detoxification systems in phagocytes and...

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Udgivet i:J Biol Chem
Main Authors: Djoko, Karrera Y., Ong, Cheryl-lynn Y., Walker, Mark J., McEwan, Alastair G.
Format: Artigo
Sprog:Inglês
Udgivet: American Society for Biochemistry and Molecular Biology 2015
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Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4521016/
https://ncbi.nlm.nih.gov/pubmed/26055706
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.R115.647099
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