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Zinc disrupts central carbon metabolism and capsule biosynthesis in Streptococcus pyogenes

Neutrophils release free zinc to eliminate the phagocytosed bacterial pathogen Streptococcus pyogenes (Group A Streptococcus; GAS). In this study, we investigated the mechanisms underpinning zinc toxicity towards this human pathogen, responsible for diseases ranging from pharyngitis and impetigo, to...

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Détails bibliographiques
Publié dans:Sci Rep
Auteurs principaux: Ong, Cheryl-lynn Y., Walker, Mark J., McEwan, Alastair G.
Format: Artigo
Langue:Inglês
Publié: Nature Publishing Group 2015
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Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC4450579/
https://ncbi.nlm.nih.gov/pubmed/26028191
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/srep10799
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