Carbon source regulates polysaccharide capsule biosynthesis in Streptococcus pneumoniae

The exopolysaccharide capsule of Streptococcus pneumoniae is an important virulence factor, but the mechanisms that regulate capsule thickness are not fully understood. Here, we investigated the effects of various exogenously supplied carbohydrates on capsule production and gene expression in severa...

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Détails bibliographiques
Publié dans:J Biol Chem
Auteurs principaux: Troxler, Lukas J., Werren, Joel P., Schaffner, Thierry O., Mostacci, Nadezda, Vermathen, Peter, Vermathen, Martina, Wüthrich, Daniel, Simillion, Cedric, Brugger, Silvio D., Bruggmann, Rémy, Hathaway, Lucy J., Furrer, Julien, Hilty, Markus
Format: Artigo
Langue:Inglês
Publié: American Society for Biochemistry and Molecular Biology 2019
Sujets:
Microbiology
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC6873171/
https://ncbi.nlm.nih.gov/pubmed/31594867
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.RA119.010764
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